This series contains mostly family correspondence concerning family affairs such as illnesses, jobs, travel, marriages, births and some current events. In a letter to his mother during the Great Depression, Sadie Campbell's son writes, "Plenty broke but it's the habit around here for everyone." A postcard from her cousin reveals that "the blueberry crop was a failure" and a letter to Lois Carpenter, whose relation to Sadie is unknown, denies Carpenter a Civil War pension due to her subsequent remarriage. Also included in this series are a considerable number of wedding and graduation invitations, postcards, and greeting cards.

The items in this series represent the many interests and vocations of Sadie Campbell and her family. Numerous documents relating to church are contained within the series: sermons, bible lessons, hymn cards, and church programs. The various clubs and organizations to which Campbell belonged are also represented, such as the Merry Wives of Cheshire Shakespeare Club, the Cheshire Cat Tearoom, and the Ladies Reading Club. Other miscellaneous items included in this series are Campbell's considerable recipe collection, unidentified registry books, a Tyrell family history, photographs, calling cards, report cards, souvenir books, event programs, and writing by various authors including Campbell's two sons, Harold and Leslie.

The bulk of this series contains documentation of Augustus Tyrell's, Sadie Campbell's father, business transactions. His business consisted of timber and talc sales and he did a considerable amount of business with Williams Manufacturing Company in Northampton, Massachusetts. This series includes records of Tyrell's land sales, business correspondence, bank checks, account books (dating back as far as 1812), receipts, checkbooks, patents and business licenses. Additionally, there are numerous warranty deeds, quit-claim deeds, contracts, mortgages, and insurance policies and claims, the majority of which belong to Tyrell. This series also includes information regarding the estate of Merila Daniels (Tyrell's aunt), tax receipts, a rental agreement between Sadie and her son, Robert, and other miscellaneous bills of Sadie Campbell and others.

This series contains printed material collected by Sadie Campbell including pamphlets and brochures covering a variety of topics: pet care, agriculture, healthcare, instruction manuals, insurance information, travel, and food preparation. Additionally, there are numerous religious publications such as Picture Lesson Paper, the New Testament, publications from the American Baptists' Society, bible lessons from the Scholars Quarterly, and other religious publications. This series also includes a town report of Cheshire, Massachusetts, newspaper clippings, catalogs, music lyrics, literary publications, a teaching manual, war ration books, and a W.C.T.U. cookbook.