Sampson Perkins was an iron molder born in Smithfield (probably Rhode Island) in 1806. By 1830 he had moved to the metalworking city of Taunton, Massachusetts where he met and married the former Almira Horton. In 1850, Perkins had accumulated $1,200 in real estate and lived in a household of five, including his wife, a daughter also named Almira, and two boarders, twenty-year-old Gustavus Thomas (also a molder) and eighteen-year-old Hannah Thomas.

Sometime in the 1860s (his company does not appear in the 1860 manufacturing census), Perkins established a small iron foundry where he made stoves and did job work for the larger Taunton companies. His shop on Water Street was situated in the middle of the Taunton River manufacturing complex. Thus, Perkins did work for such large neighboring companies as Crocker Bros. & Co., Reed and Barton, the Taunton Iron Works, American Screw Co., Phoenix Machine Co., and W.R. Potter.

Sampson Perkins & Co. disappears from the business directories as early as 1878, perhaps the result of Perkins' death.