The Elizabeth Dodge Huntington Clarke Papers consist of .5 linear ft. and are primarily related to her work on behalf of the YWCA in the U.S. and around the world, particularly in the Middle East. Materials include correspondence, newspaper clippings, publications, a published volume of memoirs, speech texts and notes, and reports. The bulk of the materials date from 1915 to 1966.

Clarke's memoir The Joy of Service chronicles her privileged New York City upbringing, initiation into YWCA work, and years in Turkey.

The correspondence contains small amounts of correspondence with U.S. and World YWCA leaders such as Ruth Rouse, Emma Bailey Speer, Doris Boss, Anna Rice, Theresa Wilbur Paist, Ruth Woodsmall, and Marion Robinson. Among the YWCA materials are various minutes, reports, clippings, and publications. The bulk of these deal with Foreign Division and World Service Council, though there is also a small amount about the Archives Committee. Materials related to the Eastern Mediterranean Federation of YWCAs include extensive proceedings of a federation conference in Jerusalem in 1926. Also included are memorial tributes Clarke wrote about her aunt, Grace Hoadley Dodge, and Emma Bailey Speer.