Birth control advocate, Women's rights advocate, Author. The bulk of the papers focus on Brush's work with Margaret Sanger and the International Planned Parenthood Federation. The collection includes first-hand accounts of Margaret Sanger's work; research and writings on Japanese women; research, questionnaires, and manuscript for her book on menopause; and reports, correspondence and photographs on the birth control missionary work of Sanger and Brush in various countries. Correspondents include C.P. Blacker, Barbara and George Cadbury, Dr. Clarence J. Gamble, Margaret Grierson, Vera Houghton, Shidzue Ishimoto Kato, Edris Rice-Wray, Margaret Sanger, and Ellen Watamull. The Dorothy Hamilton Brush Papers are closely related to the Margaret Sanger Papers.

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Permission to publish reproductions or quotations beyond "fair use" must also be obtained from the Sophia Smith Collection as owners of the physical property.