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This series contains letters written by Lane in 1861-1863, 1910, and 1912. Of particular note are letters dating from 1861-1863 while she was a student at Mount Holyoke Female Seminary. These nine letters are addressed to her brothers Charles T. Haynes, a student at Amherst College, and John Haynes, a soldier with Union forces during the Civil War. Lane discusses many aspects of her life at the Seminary, including the rules, her course work in botany, domestic work on campus, and prayer meetings. These letters also include references to the war and its impact on students. For example, she mentions the death of a student's father in the war and another student's decision to go south to teach freed slaves. Typed transcripts for three of these letters (circa September 1861, circa April 1862, and April 2, 1863) are part of this series.

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This series contains a newspaper article, 1889, and an essay, 1907 by Lane. The newspaper article, from the "Hampshire Gazette," July 9, 1989, is a printing of a paper read at the meeting of the "National Alumnae Association at the late Commencement." It discusses the history of her alma mater, Mount Holyoke College, and focuses on the school's transformation from a Seminary to College. The 1907 essay, entitled "Mount Holyoke's Golden Age," was read by Lane at a meeting of the Hampshire County Mount Holyoke Alumnae Association. It describes her time at the school 1861-1868, and the changes that occured between 1857 and 1867.

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This series contains excerpts of letters, 1861 and a pin. The letters were written by Lane's brother, Charles T. Haynes, to their brother, John Haynes on September 26 and October 18, 1861. They discuss visits to Lane while she was a student at Mount Holyoke Female Seminary. The pin was worn by her husband, John William Lane, when he was a chaplain associated with the United States Christian Commission during the Civil War.

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This series consists of notes, clippings, and articles, chiefly relating to Lane's life and dating from about 1908-1922. This material contains copies of articles concerning her death. The series also include notes about her and clippings concerning her husband, John William Lane.

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This series consists of two formal photographs of Lane taken in July 1868 while she was at Mount Holyoke Female Seminary.