The bulk of the collection consists of incoming and outgoing correspondence dating chiefly from George D. Pratt's undergraduate years and some years after. Correspondents include Amherst College physician and professor of physical education and hygiene Edward "Old Doc" Hitchcock (regarding Mr. Pratt's donation of the college infirmary, ca. 1896-1898), Helen "Nellie" Sherman (his future wife), and his brothers Bert (i.e., Herbert, AC 1895), John (AC 1896) and Fred (AC 1887), writing from college. Included herein is a small leather booklet given to Pratt by his father for Christmas in 1882, intended as a ledger for his personal finances. The collection also includes one family photographic portrait and an oversize photograph album showing family mountain vacations and other travels, as well as Harvard ROTC military training exercises in the summer of 1918. Finally, there is a single issue of the magazine Survey Graphic, February 1923, featuring an article on Helen Sherman Pratt.

This collection is organized into two series:

• Correspondence, ca. 1882-1898
• Photographs and Printed Matter, 1917-1925